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Pilot Project Application Form

Pilot Project Program Description

Comprehensive Alcohol Research Center/Louisiana State University Health Sciences Center
Request for Applications for Pilot Project Funding
FUNDING OPPORTUNITY:
The Comprehensive Alcohol Research Center is an NIAAA-sponsored P60 grant that has a Pilot Project Program. Awards are typically less than $50,000 per project for a 12-month period. The number of pilot awards is determined by funds available. A second year of funding will be considered if money is available, and strongly justified by progress in the first year. A second year of funding will be competitive with new applications.

SUBMISSION DEADLINE: Deadline is closed at this time.

PURPOSE:
The purpose of the CARC Pilot Project Program is to expand interest in the alcohol research field and explore new alcohol research directions that are thematically consistent with the focus of the CARC. The goal of the program is that the pilot studies will evolve into independently funded research projects. The CARC conducts research to understand the impact of alcohol abuse on HIV disease progression and its complications using our chronic alcohol/SIV infection model in rhesus macaques with and without anti-retroviral therapy. other models of infection, inflammation and trauma and human studies that will translate findings into health care practices. Applications should address the impact of alcohol on HIV transmission or the disease by using the rhesus macaque model or performing translational studies in humans.
PROPOSAL BASICS:
Application instructions: See application form.

Research Plan:NIH style Biosketch that includes Other Support for all key personnel.
Other Support should indicate percent effort and total direct costs for duration on the grant or contract.
Budget Instructions: No faculty salary support for faculty is allowed. Technician, and postdoctoral salary support is allowed.
Instructions for Submitting Proposals:  Please note: This funding mechanism does not need to be routed through the Office of Research Services at LSUHSC for signatures.
Review/Evaluation Process: The review committee consists of the CARC Intramural Center Committee (ICC), other key personnel of the CARC, and if needed other experts pertinent to the subject matter of an application. Decisions to ask for outside reviewers will be at the discretion of the ICC. Pre- and postdoctoral fellows supported by our T32 grant may also participate in the review process for training purposes. In the review process, interview and/or seminar-like presentations by applicants may be used, especially if ICC members are not familiar with the applicant.
Criteria for Review/Evaluation of Applications: The review committee will prioritize applications using the following criteria:

  • Significance – Does the study address an important problem to the alcohol research field related to focus of the CARC;
  • Approach – Are the overall approach, design, methods and analysis adequately developed and appropriate to address the aims of the study;
  • Innovation – Does the study use novel approaches, challenge existing ideas or develop new methodologies;
  • Investigators – Is he/she appropriately trained and experienced the research area to carry out the proposed work, and does the investigator have the track record that would warrant extramural funding based on the data obtained;
  • Resources and Environment – Does the PI have adequate infrastructure to address the technical needs of the study.

Funding decision: The ICC will submit written evaluations of each application to the Director along with a rank order for the applications received. With this information he will make the final decision about funding. The goal is to make funding decisions by November 15th. Approval is also contingent upon timely approval by appropriate institutional committees such as Institutional Review Board for human subject research, Institutional Animal Care and Use Committee, Institutional Biosafety Committee, Tulane Resource Allocation Committee (assignment of nonhuman primates at the TNPRC), etc. Funding will start December 1 contingent on the ability of the investigator to start the project. At the discretion of the Director a project can be recalled if the above mentioned approvals are not obtained in a timely manner that jeopardizes the ability of the investigator to make meaningful progress.

Monitoring, Oversight and Continuation Decisions: Members of the ICC will work with the PI of pilot projects as needed to insure progress is being made and when PI are applying their expertise to an alcohol-related question for the first time. A Progress Report must be submitted to ICC members on August 1st, 2015. The Project PIs are also expected to attend monthly CARC meetings and seminars sponsored by the CARC. They will also will be expected to present progress at CARC meetings. For Pilot Project PIs at distant sites, discussions can take place over the phone and they will be able to attend CARC meetings by teleconferencing. Projects can be funded for a second year at the discretion of the ICC and Director. Such decisions are based on progress, a judgment on the potential for extramural funding, and on the quality of the new applicant pool. If a project is identified for two years of funding, review by the ICC will take place prior to the second year to insure that progress is being made and that funds will be available for a second year of funding.